Effect of bronchial blood flow on pulmonary artery wedge pressure with pulmonary embolism
作者:
BRUCE BUTLER,
ROBERT DRAKE,
BRIAN HILLS,
期刊:
Critical Care Medicine
(OVID Available online 1986)
卷期:
Volume 14,
issue 5
页码: 495-498
ISSN:0090-3493
年代: 1986
出版商: OVID
数据来源: OVID
摘要:
Discrepancies between pulmonary artery wedge pressure (WP) and left atrial pressure (LAP) occur with pulmonary embolism. Theoretically, this discrepancy could be affected by the bronchial circulation or by the type of embolus. To test this in dogs, we determined the effects of embolism induced by glass beads and by air upon the WP with intact vs. ligated bronchial blood flow to the left lower lobe. For those animals receiving pulmonary air infusions, the pulmonary artery pressure, WP, and pulmonary vascular resistance showed significant (p< .05) elevations with no change in LAP. There were no changes in these values when the bronchial blood flow was interrupted. When glass beads (120 ±) were injected into the left lower lobe, the pulmonary artery pressure and pulmonary vascular resistance rose as in the air emboli groups (p< .05); however, WP remained at control values and approximated LAP. Obstructing the bronchial blood flow did not change this response. We conclude that the discrepancy between WP and LAP depends upon the type of embolus and is not affected by bronchial blood flow.
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