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Amino acid metabolism in liver disease

 

作者: Eggert Holm,   Oliver Sedlaczek,   Eva Grips,  

 

期刊: Current Opinion in Clinical Nutrition and Metabolic Care  (OVID Available online 1999)
卷期: Volume 2, issue 1  

页码: 47-53

 

ISSN:1363-1950

 

年代: 1999

 

出版商: OVID

 

数据来源: OVID

 

摘要:

The impairment of transsulphuration during methionine degradation in hepatic failure can be counteracted by treatment withS-adenosylmethionine. Regarding the pathogenesis of hepatic encephalopathy, no convincing evidence exists for tryptophan, glutamine or glutamate being involved. Portal-systemic shunting-induced hyperammonaemia may reduce plasma branched-chain amino acids. The glucose effect on urea synthesis does not exist in cirrhosis.

 



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