Some Biochemical Aspects of the Protective Effect of Strontium Chloride on Gamma-Irradiated Rats
作者:
F. A. Fahim,
R. M. Yousri,
H. M. Roushdy,
M. I. Abady,
期刊:
Isotopenpraxis Isotopes in Environmental and Health Studies
(Taylor Available online 1991)
卷期:
Volume 27,
issue 7
页码: 318-324
ISSN:0021-1915
年代: 1991
DOI:10.1080/10256019108622556
出版商: Taylor & Francis Group
关键词: alkaline phosphatase;aminotransferases;enzyme activity;enzymes;gamma radiation;glycogen;lactate dehydrogenase;life span;liver;strontium chlorides;survival time;whole-body
数据来源: Taylor
摘要:
The effect of treatment with SrCl2(10 mg/100 g rat) on rats 15 minutes prior to whole body γ-irradiation (7,5 Gy) was studied. The hazardeous effect of irradiation were greatly corrected in the treated group. The hyperglycemic effect and liver glycogen accumulation in the untreated group decreased to normal level. The enzymatic activities of serum alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase and lactate dehydrogencase were greatly affected showing insignificant changes in the treated group of animals. Life span calculated on 50% survival was also significantly elongated by 36.3%. These results show the potentiality of SrCl2as a radioprotective agent which was not used before.
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