Thrombosis and Infection: A Case of Transient Anti-Cardiolipin Antibody Associated with Pylephlebitis
作者:
Angelike Liappis,
Afsoon Roberts,
Arnold Schwartz,
Gary Simon,
期刊:
The American Journal of the Medical Sciences
(OVID Available online 2003)
卷期:
Volume 325,
issue 6
页码: 365-368
ISSN:0002-9629
年代: 2003
出版商: OVID
关键词: Anti-cardiolipin antibody;Thrombosis;Bacteremia;Pylephlebitis;Mesenteric vein,Bacteroides
数据来源: OVID
摘要:
Infections withBacteroidesspecies have been noted to occur in association with cases of thrombophlebitis. This association has led to the speculation that the microorganisms themselves may contribute to the pathogenesis of thrombus formation through elaborated enzymes, including heparinases, or by interactions between the clotting cascade and the unique structure of theBacteroideslipopolysaccharide. Anti-phospholipid antibodies have been linked with hypercoagulable states and thrombus formation. Although a number of infections have been associated with the transient production of anti-cardiolipin antibodies, the effect the antibodies may have in contributing to thrombus formation is not well understood. The occurrence ofBacteroidesspecies infection with transient anti-cardiolipin antibody has not been previously reported.
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