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A Convenient Synthesis of 2′- OR 4′-Hydroxycocaine

 

作者: Satendra Singh,   GaroP. Basmadjian,   Kwasi Avor,   Buddi Pouw,   ThomasW. seale,  

 

期刊: Synthetic Communications  （Taylor Available online 1997）
卷期: Volume 27, issue 22  

页码: 4003-4012

 

ISSN:0039-7911

 

年代: 1997

 

DOI:10.1080/00397919708005923

 

出版商: Taylor & Francis Group

 

数据来源: Taylor

 

摘要:

Abstract: A short, convenient and efficient synthesis of 2′- or 4′-hydroxycocaine is described. The key step involved selective hydrolysis/transesterification of the acetoxy group of 2′- or 4′-acetoxycocaine in methanol saturated with dry HCl gas.

 

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