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A Study of HLA Antigen Distribution in Families with Atopic Dermatitis

 

作者: Rona M. MacKie,   Heather M. Dick,  

 

期刊: Allergy  （WILEY Available online 1979）
卷期: Volume 34, issue 1  

页码: 19-23

 

ISSN:0105-4538

 

年代: 1979

 

DOI:10.1111/j.1398-9995.1979.tb01996.x

 

出版商: Blackwell Publishing Ltd

 

关键词: antigens;atopy;haplotype;HLA;IgE

 

数据来源: WILEY

 

摘要:

Seventeen children presenting with atopic dermatitis were HLA typed together with their parents and siblings. A total of 89 individuals was studied. No close link between HLA antigen distribution and clinical expression of atopy was demonstrated, and 14 HLA identical but disease‐free siblings were identified. An increase in the A1 B8 haplotype was observed in the families as a whole by comparison with a large control serie

 

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