Increased numbers of mast cells in the hyperplastic buccal mucosa of the zinc‐deficient rat
作者:
M. E. Kravich,
J. Meyer,
J. P. Waterhouse,
期刊:
Journal of Oral Pathology&Medicine
(WILEY Available online 1981)
卷期:
Volume 10,
issue 1
页码: 22-31
ISSN:0904-2512
年代: 1981
DOI:10.1111/j.1600-0714.1981.tb01244.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
AbstractSix weanling male Sprague Dawley rats were fed a diet containing 0.4 ppm Zn and seven were fed an identical diet except for 40 ppm Zn. After 4 weeks, specimens of buccal mucosa in the region facing the molar teeth were removed. Paraffin sections, cut at 6 μ, were stained with toluidine blue, and tracings made of five sections per animal, spaced no less than 60 μm apart. Counts of mast cells over a measured length of section were made in a superficial zone of the lamina propria of 50 μm width and a deeper zone of 250 μ width.The average number of mast cells per mm in the subepithelial zone of the experimental animals was 15.4, the range 9.2–33.1. The control average was 4.0; the range was 2.9–5.3. No increase was found in the deeper zone.The epithelium was parakeratotic and its thickness was increased two‐fold. In the peripheral portion of the section, cellular and keratin layers were evenly increased in thickness, but in the central portion a disproportionate, nearly four‐fold increase occurred in the keratin layer and a lesser increase in the cel
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