Changes with Age in the Number and Size of Myelinated Axons in the Rat L4Dorsal Spinal Root
作者:
Rupanagudi S. Rao,
G. Krinke,
期刊:
Cells Tissues Organs
(Karger Available online 1983)
卷期:
Volume 117,
issue 3
页码: 187-192
ISSN:1422-6405
年代: 1983
DOI:10.1159/000145786
出版商: S. Karger AG
关键词: Dorsal spinal root;Rat;Aging;Demyelination;Axon atrophy;Neuronal dwindling;Quantitation
数据来源: Karger
摘要:
The number and size of myelinated axons in the L4 dorsal spinal root were determined in young rats and compared to those in the adult (older than 1 year) and in the old rats (older than 2 years). While the total number of myelinated axons was about the same at all ages, the average overall axon diameter showed a growth-related increase in adult animals, followed by a decrease reflecting senile atrophy in old rats. It is suggested that in aging laboratory rats the extent of axon shrinkage could account for the occurrence of secondary radicular demyelination.
点击下载:
PDF
(784KB)
返 回