Virus-associated lymphomas
作者:
Ethel Cesarman,
Enrique Mesri,
期刊:
Current Opinion in Oncology
(OVID Available online 1999)
卷期:
Volume 11,
issue 5
页码: 322-322
ISSN:1040-8746
年代: 1999
出版商: OVID
数据来源: OVID
摘要:
Epstein-Barr virus, Kaposi’s sarcoma-associated herpesvirus/human herpesvirus 8, and human T-cell lymphotrophic virus are viruses that are implicated in lymphoid neoplasia in humans. Their association with specific subsets of lymphomas suggests that they play an important, although not sufficient, etiologic role in their development. Current knowledge suggests that these viruses contribute to lymphomagenesis by subverting the host-cell molecular machinery to deregulate cell growth and survival. In this article, the basic information and recent developments that have contributed to our understanding of viral lymphomagenesis are reviewed.
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