Immunohistochemical Localization of Five Classes of Intermediate Filament in a Benign Pelvic Soft Tissue Tumor of Rhabdoid Appearance
作者:
Yoichi Nakazato,
Junko Hirato,
Yukihiro Nakanishi,
Osamu Tamaki,
Chiaki Yazaki,
期刊:
Pathology International
(WILEY Available online 1991)
卷期:
Volume 41,
issue 1
页码: 65-72
ISSN:1320-5463
年代: 1991
DOI:10.1111/j.1440-1827.1991.tb03274.x
出版商: Blackwell Publishing Ltd
关键词: Benign pelvic tumor;Immunohistochemistry;Coexpression;Intermediate filament;Rhabdoid cell
数据来源: WILEY
摘要:
A benign pelvic soft tissue tumor from a 50 year old woman was examined by immunohistochemistry and electron microscopy. The tumor cells had abundant eosinophilic cytoplasm with a hyaline appearance, which was filled with large aggregates of intermediate‐sized filaments (IF). The cells were positively immunostained by antibodies against cytokeratin, vimentin, desmin, glial fibrillary acidic protein, and neurofilament proteins. This case represents an extreme example of the simultaneous expression of IF by neoplastic cells, and exemplifies the limited applicability of immunohistochemical detection of IF antigens for pathological diagnosis of neoplasms. Acta Pathol Jpn 41: 65–72, 1
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