Renal involvement in hematological disorders: monoclonal immunoglobulins and nephropathy
作者:
Pierre Ronco,
Béatrice Mougenot,
Guy Touchard,
Jean-Louis Preud'homme,
Pierre Aucouturier,
期刊:
Current Opinion in Nephrology and Hypertension
(OVID Available online 1995)
卷期:
Volume 4,
issue 2
页码: 130-138
ISSN:1062-4821
年代: 1995
出版商: OVID
数据来源: OVID
摘要:
The study of monoclonal immunoglobulin-associated nephropathies is useful for analyzing the physicochemical properties of immunoglobulin components responsible for their deposition in the kidney. Notable advances include the first description of truncated heavy-chain deposition disease, characterization of protease resistance and binding properties of immunoglobulin light chains involved in myeloma-associated Fanconi's syndrome and cast nephropathy, and identification of hepatitis C virus as a plausible causative agent of the so-called essential mixed cryoglobulinemias.
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