Nonlinear Dependence of Fish Bioconcentration onn-Octanol/Water Partition Coefficient
作者:
S. Bintein,
J. Devillers,
W. Karcher,
期刊:
SAR and QSAR in Environmental Research
(Taylor Available online 1993)
卷期:
Volume 1,
issue 1
页码: 29-39
ISSN:1062-936X
年代: 1993
DOI:10.1080/10629369308028814
出版商: Taylor & Francis Group
关键词: Bioconcentration;BCF;fish;bilinear model;linear model;parabolic model
数据来源: Taylor
摘要:
The log-log relationship between the bioconcentration tendency of organic chemicals in fish and then−octanol/water partition coefficients breaks down for very hydrophobic compounds. The use of parabolic and bilinear models allows this problem to be overcome. The QSAR equation log BCF = 0.910 logP- 1.975 log (6.8 10−7P+ 1) - 0.786 (n= 154;r= 0.950;s= 0.347;F= 463.51) was found to be a good predictor of bioconcentration in fish.
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