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Nonlinear Dependence of Fish Bioconcentration onn-Octanol/Water Partition Coefficient

 

作者: S. Bintein,   J. Devillers,   W. Karcher,  

 

期刊: SAR and QSAR in Environmental Research  (Taylor Available online 1993)
卷期: Volume 1, issue 1  

页码: 29-39

 

ISSN:1062-936X

 

年代: 1993

 

DOI:10.1080/10629369308028814

 

出版商: Taylor & Francis Group

 

关键词: Bioconcentration;BCF;fish;bilinear model;linear model;parabolic model

 

数据来源: Taylor

 

摘要:

The log-log relationship between the bioconcentration tendency of organic chemicals in fish and then−octanol/water partition coefficients breaks down for very hydrophobic compounds. The use of parabolic and bilinear models allows this problem to be overcome. The QSAR equation log BCF = 0.910 logP- 1.975 log (6.8 10−7P+ 1) - 0.786 (n= 154;r= 0.950;s= 0.347;F= 463.51) was found to be a good predictor of bioconcentration in fish.

 

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