1.A study was made of the reactions of perfluoroacetone with alcohols, organometallic compounds, and compounds containing mobile hydrogen.2.Hemiketals, ketals, tertiary alcohols, symmetric and unsymmetric diols, andβ-hydroxy acids containing two trifluoromethyl groups were synthesized.3.4,4,4-trifluoro-3-hydroxy-3-(trifluoromethyl) butyrophenone, obtained by the hydration of 1,1,1-trifluoro-4-phenyl-2-(trifluoromethyl-3-butyn-2-ol, decomposes when heated into perfluoroacetone and acetophenone with cleavage of a C-C bond. Decomposition in this way, which is unusual forβ-hydroxy ketones, indicates the immobility of a hydroxy group attached to a carbon carrying two trifluoromethyl groups.4.When perfluoroacetone is heated with phenol or o-cresol in anhydrous hydrogen fluoride solution, 4,4′-(hexafluoroisopropylidene) diphenol or 4,4′-(hexafluoroisopropylidene) di-o-cresol, respectively, is f