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Folarographic Behaviour of Nitrendipine

 

作者: J.A. Squella,   I. Lemus,   S. Perna,   L.J. Nuñtez-Vergara,  

 

期刊: Analytical Letters  （Taylor Available online 1988）
卷期: Volume 21, issue 12  

页码: 2293-2305

 

ISSN:0003-2719

 

年代: 1988

 

DOI:10.1080/00032718808059910

 

出版商: Taylor & Francis Group

 

关键词: Differential pulse polarography;Nitrendipine;Pharmaceuticals

 

数据来源: Taylor

 

摘要:

Nifedipine, a calcium antagonist drug, proceduces a well-defined polarographic wave due to the four-electron, four-proton reduction of the nitro group. This peak is diffusion-controlled and shows a linear dependence on the Nitrendipine concentration. This behaviour is used for analytical purposes in determining Nitrendipine content in commercial preparations. The method is sensitive enough to be applied to single tablet, assays.

 

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