Corneal Permeability of 5-Iodo-2′-deoxycytidine
作者:
V. Sincholle,
J.P. Conduzorgues,
B. Mbatchi,
J.P. Masse,
期刊:
Nucleosides and Nucleotides
(Taylor Available online 1985)
卷期:
Volume 4,
issue 1-2
页码: 225-226
ISSN:0732-8311
年代: 1985
DOI:10.1080/07328318508077862
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
IDC is an antiherpetic agent which exhibits some advantages when compared to IDU, a better solubility in water allows higher concentrations for eye-drops, an improved antiviral activity by a greater specificity since the compound is phosphorylated by a viral induced specific thymidine-kinase and a subsequent lower toxicity for host-cells (KURlMOTO, 1969; De CLERCQet al., 1980).
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