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Lumpectomy and Breast Irradiation for Breast Cancer Arising After Previous Radiotherapy for Hodgkin’s Disease or Lymphoma

 

作者: Melvin Deutsch,   Kristina Gerszten,   William Bloomer,   Eli Avisar,  

 

期刊: American Journal of Clinical Oncology: Cancer Clinical Trials  (OVID Available online 2001)
卷期: Volume 24, issue 1  

页码: 33-34

 

ISSN:0277-3732

 

年代: 2001

 

出版商: OVID

 

关键词: Hodgkin’s disease;Lymphoma;Second malignancy;Breast conservation therapy

 

数据来源: OVID

 

摘要:

Twelve women treated with radiotherapy with or without chemotherapy for Hodgkin’s disease (11 patients) and non-Hodgkin’s lymphoma (1 patient) and in whom breast cancer subsequently developed 10 to 29 years later were treated with lumpectomy and breast irradiation, 5,000 cGy/25–30 fractions to the whole breast and 900 cGy to 1,000 cGy/5 boost to the operative area. Six also received adjuvant chemotherapy for breast cancer. Breast irradiation was well tolerated without any unusual acute or chronic sequelae. All women had a good to excellent cosmetic result. Ten women are alive and well 1 to 174 months (median: 46) from completion of breast irradiation. Two women died with distant metastasis but without local recurrence. Breast conservation therapy with radiotherapy is not contraindicated in the woman who has previously been treated with radiotherapy for Hodgkin’s disease or lymphoma.

 

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