Two Different Isoforms of Desmocollin Are Recognized by Autoantibodies in Various Types of Pemphigus
作者:
T. Hashimoto,
T. Ebihara,
T. Nishikawa,
期刊:
Dermatology
(Karger Available online 1994)
卷期:
Volume 189,
issue 1
页码: 124-125
ISSN:1018-8665
年代: 1994
DOI:10.1159/000246952
出版商: S. Karger AG
关键词: Cadherin;Desmocollin;Desmosome;Intercellular IgA vesiculopustular dermatosis;Pemphigus
数据来源: Karger
摘要:
We have previously reported that, in addition to well-known pemphigus antigens (desmoglein and pemphigus vulgaris antigen), desmocollin (Dsc), another desmosomal cadherin, is recognized by certain pemphigus sera. Furthermore, we noticed that two Dsc species with a slightly different relative molecular weight were recognized by various pemphigus sera. This difference may contribute to the different clinicopathological features between the subcorneal pustular dermatosis type and the intraepidermal neutrophilic IgA dermatosis type of intercellular IgA vesiculopustular dermatosis.
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