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In vivomagnetic resonance imaging and spectroscopy of humans with a 4 t whole‐body magnet

 

作者: H. Barfuss,   H. Fischer,   D. Hentschel,   R. Ladebeck,   A. Oppelt,   R. Wittig,   W. Duerr,   R. Oppelt,  

 

期刊: NMR in Biomedicine  (WILEY Available online 1990)
卷期: Volume 3, issue 1  

页码: 31-45

 

ISSN:0952-3480

 

年代: 1990

 

DOI:10.1002/nbm.1940030106

 

出版商: John Wiley&Sons, Ltd.

 

数据来源: WILEY

 

摘要:

AbstractA research‐type 4 T whole‐body magnet, built by Siemens AG, Erlangen, FRG, was used to investigate magnetic resonance at high field strengths. Designs for head and body coils operating at 170 MHz are described. Proton images of the human head and body are degraded by dielectric resonances and penetration effects. The nature of the dielectric resonances was demonstrated in phantoms containing distilled and saline doped water. Radiation damping at 170 MHz generates secondary echoes after a spin echo sequence. This effect was observed in phantoms and with reduced amplitude in the human head. Hydrogen spectra of the human head were selected utilizing stimulated and spin echoes. The latter technique allows the volume size to be reduced to 1 cm3. Examples of brain tumors that have been routinely investigated with volumes of 8 cm3are given. Natural abundance carbon and phosphorus spectra of muscle and liver demonstrate the expected increase in spectral resolution and signal to noise ratio. Carbon spectra from the liver show the glycogen signal. Fluorine spectroscopy was used to study the time course of the absorption and emptying of a fluorinated antibiotic from the human stom

 

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