Relationship between plasma and platelet phospholipid fatty acid composition in healthy subjects
作者:
PriscoD.,
PanicciaR.,
BandinelliB.,
FilippiniM.,
FrancalanciI.,
BrunelliT.,
GiustiB.,
AbbateR.,
期刊:
Platelets
(Taylor Available online 1996)
卷期:
Volume 7,
issue 1-2
页码: 69-73
ISSN:0953-7104
年代: 1996
DOI:10.3109/09537109609079512
出版商: Taylor&Francis
数据来源: Taylor
摘要:
In order to furtherly clarify the mechanisms regulating the fatty acid composition of platelet phospholipids the relationships between the fatty acid composition of major phospholipid fractions from plasma and platelets were investigated in 30 healthy male subjects. Strict correlations between all but two plasma and platelet fatty acids were observed for phosphatidylcholine (PC) (r = 0.51-0.95, at leastP<0.01), whereas only poor correlations were found for the other fractions. These results suggest that the direct transfer of PC molecules from plasma to platelet membrane is a pivotal mechanism for renovation of platelet PC fatty acids, while other mechanisms appear to play a major role for renovation of other phospholipid fractions of the platelet membrane.
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