Congenital Lipoprotein Lipase Deficiency in Hyperlipemic Kitten Siblings
作者:
John E. Bauer,
Jill W Verlander,
期刊:
Veterinary Clinical Pathology
(WILEY Available online 1984)
卷期:
Volume 13,
issue 1
页码: 7-11
ISSN:0275-6382
年代: 1984
DOI:10.1111/j.1939-165X.1984.tb00626.x
出版商: Blackwell Publishing Ltd
关键词: Kitten;hyperlipemia;lipoprotein lipase;lipoproteins;triglyceride;cholesterol;cat.
数据来源: WILEY
摘要:
SummaryThe nature of the hyperlipemia in two 3‐week‐old male kittens, one of which was presented with the owner's complaints of retarded growth and white streaks on its eyes, was studied. Hypertriglyceridemia, hyper‐cholesterolemia, and reduced Post‐Heparin Plasma Lipolytic Activities (PHPLA) were observed in both animals. One of the kittens, however, was more severely affected and in addition, had lipemia retinalis and a marked lactescent, hyperchylomicronemic serum in spite of a short‐term fast before sampling. These findings are strikingly similar to those found in human Type I hyperlipoproteinemia due to familial Lipoprotein Lipase (LPL) deficiency. Diagnosis of persistent hyperlipemic syndromes in kittens should include the possibility of LPL deficiency as determined by PHPLA mea
点击下载:
PDF
(413KB)
返 回