SummaryShortly alter the onset ol juvenile diabetes. 10 to 30 of patients recover from the absolute exogenous insulin dependence. I his remission period is transient. Insulin secretion during insulinotherapy can l>c assessed by the measurement of plasma CPeptide levels. I his allows to recognile the existence I complete or partial remission. I he frequency and duration of this«honeymoon period»of the juvenile diabetes is enhanced by an appropriate insulin treatment. I lie remission may be followed by prolonged periods during which a residual insulin secretion is detectable, the latter is insufficient to maintain normal blood glucose levels, but seems to be correlated with a good control of the disease. I his concept is confirmed by personal data.