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Chemotherapy, radiotherapy, and immunotherapy of colorectal neoplasia

 

作者: Irving Taylor,  

 

期刊: Current Opinion in Gastroenterology  (OVID Available online 1993)
卷期: Volume 9, issue 1  

页码: 28-33

 

ISSN:0267-1379

 

年代: 1993

 

出版商: OVID

 

数据来源: OVID

 

摘要:

Adjuvant therapy for colorectal cancer continues to excite significant interest, particularly for “high-risk” patients in whom systemic 5-fluorouracil and leucovorin should be considered. However, intraportal 5-fluorouracil and intraperitoneal chemotherapy require further assessment. For rectal cancer, combined chemo- and radiotherapy have demonstrated survival advantages. In patients with advanced or recurrent disease, modification of 5-fluorouracil with folinic acid and locoregional infusion treatment have both demonstrated efficacy. In general immunotherapy, studies have so far proved disappointing for advanced colorectal cancer.

 

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