The significant effect of fat emulsion intralipid‐10% mixing on lasing behaviors of liquid microdroplets was studied using rhodamine 6G dye. This highly scattering medium allows one to make the high‐gain laser dye‐soft scatterers microsystems that can provide well‐defined lasing threshold and one‐order or more magnitude enhancement of emission intensity with suitable (optimum) conditions of the mixing ratio, in comparison with original neat‐dye lasing microdroplets. We also present and discuss the measured results of input–output intensities for different dye concentrations and dye‐intralipid mixing ratios, and microscope images of spatial distribution of emission from both the microdroplets containing neat‐dye and dye‐intralipid mixture. ©1996 American Institute of Physics.