Placebo-controlled study of pramiracetam in young males with memory and cognitive problems resulting from head injury and anoxia
作者:
McLeanAlvin,
CardenasDiana D.,
BurgessDonna,
GamzuElkan,
期刊:
Brain Injury
(Taylor Available online 1991)
卷期:
Volume 5,
issue 4
页码: 375-380
ISSN:0269-9052
年代: 1991
DOI:10.3109/02699059109008110
出版商: Taylor&Francis
数据来源: Taylor
摘要:
The current study evaluated under double-blind placebo-controlled conditions, the safety and efficacy of 400 mg pramiracetam sulphate TID in treating memory and other cognitive problems of males who have sustained brain injuries. The results of the study indicate that subject performance in measures of memory, especially delayed recall, evidenced clinically significant improvements after the administration of pramiracetam sulphate as compared to placebo. This improvement was maintained during an 18-month open-trial period on the medication as well as during a 1-month follow-up period after the pramiracetam was discontinued.
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