Hemoglobins AIDA (α64 ASP→ASN) and D-Los Angeles (β121 Glu→Glu) in an Asian-Indian Family
作者:
BunnH. F.,
AltmanA. J.,
StanglandK.,
FirsheinS. I.,
ForgetB.,
SchmidtG. J.,
JonesR. T.,
期刊:
Hemoglobin
(Taylor Available online 1978)
卷期:
Volume 2,
issue 6
页码: 531-540
ISSN:0363-0269
年代: 1978
DOI:10.3109/03630267809005354
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Hemoglobins D-Los Angeles (β121 Gin) and Aida (α64 Asn) were encountered in an Asian Indian, unassociated with any clinical manifestations. These hemoglobins had normal oxygen affinities and were stable to heat and isopropanol. The ratio ofαchain synthesis toβchain synthesis was close to unity. The identical change in isoelectric points of the two variants produced an interesting electrophoretic pattern.The coexistance of more than one hemoglobin variant in an individual or family has provided valuable
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