AbstractBone marrow biopsies, aspirates and smears are important procedures for diagnoses. Morphological abnormalities like focal lesions (lymphomas, granulomas) cannot be found in smears but will be present in the biopsy. Superior histologic preparations are essential for diagnostic interpretation of bone marrow. Appropriate histologic procedures for the preparation of bone marrow sections are presented in detail. Methods of fixation, processing, sectioning, routine H&E, iron stains and certain“special stains”are described.