Open‐Eye Corneal Swelling Secondary to Hydrogel Contact Lens Wear
作者:
BARRY WEISSMAN,
PAUL BLAZE,
SUE INGLES,
NOEL WHEELER,
期刊:
American Journal of Optometry and Physiological Optics
(OVID Available online 1988)
卷期:
Volume 65,
issue 4
页码: 272-276
ISSN:0093-7002
年代: 1988
出版商: OVID
关键词: oxygen;oxygen transmissibility;contact lenses
数据来源: OVID
摘要:
Three hydrogel contact lenses of measured oxygen transmissibility (Dk/L = 20, 12, and 6 x 10−9cm ml O2/s ml mm Hg, respectively) were used to induce central corneal swelling as measured by optical pachometry in five human subjects under open-eye conditions (8 h wear). Both contact lenses with higher Dk/L values induced mean central corneal swelling of about 1.5%. The lower Dk/L lens induced a mean central corneal swelling of 2.2%. However, statistical analysis of the differences in central corneal swelling between the lens-wearing and the control eyes indicates that swelling induced by the higher Dk/L lenses is not identical, and indicates that even a Dk/L of 20 x 10−9is insufficient to reduce corneal swelling to zero. This suggests that the “critical oxygen tension” (COT) could be in excess of 20 to 40 mm Hg, but not necessarily as high as 70 mm Hg.
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