首页   按字顺浏览 期刊浏览 卷期浏览 Significance of Diagnostic Parameters in [13C]Octanoic Acid Gastric Emptying Breath Tes...
Significance of Diagnostic Parameters in [13C]Octanoic Acid Gastric Emptying Breath Tests*

 

作者: B. Schommartz,   D. Ziegler,   P. Schadewaldt,  

 

期刊: Isotopes in Environmental and Health Studies  (Taylor Available online 1998)
卷期: Volume 34, issue 1-2  

页码: 135-143

 

ISSN:1025-6016

 

年代: 1998

 

DOI:10.1080/10256019708036341

 

出版商: Taylor & Francis Group

 

关键词: Breath test;carbon 13;diabetes;gastric emptying;human;[13C]octanoic acid

 

数据来源: Taylor

 

摘要:

Two novel characteristic parameters, the latency time (tlat) and the ascension time (tasc), are proposed for evaluation of non-invasive [13C]octanoic acid breath tests for assessment of the gastric emptying of solids. In breath tests performed in control subjects (n= 30) and diabetic patients (n= 100), the usefulness of these parameters was compared to conventional parameters,i.e., gastric half emptying-timet1/2,b) and lag phase (tlag,b). The proposed parameters were only loosely correlated (controls,r= 0.199; diabetics, 0.616). A strong correlation was found between the conventional parameters (controls,r= 0.891; diabetics,r= 0.962). Based on the conventional method, 36 patients were suspicious of delayed gastric emptying including 24 patients which exhibited a simultaneous delay in both parameters. Using the new parameters, a total of 46 patients were suspicious of delayed gastric emptying with 15 and 20 having isolated delay intlatandtasc, respectively. We conclude that the novel parameters may be more appropriate for examination of the different phases of gastric emptying and for evaluation of gastric emptying disturbances in diabetic patients than the parameters conventionally used for this purpose.

 

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