Comprehensive Study of Haemostasis in Chronic Uraemia
作者:
F. Panicucci,
A. Sagripanti,
E. Pinori,
M. Vispi,
L. Lecchini,
G. Barsotti,
S. Giovannetti,
期刊:
Nephron
(Karger Available online 1983)
卷期:
Volume 33,
issue 1
页码: 5-8
ISSN:1660-8151
年代: 1983
DOI:10.1159/000182894
出版商: S. Karger AG
关键词: Haemostasis abnormalities;Chronic uraemia;Haemorrhagic syndrome
数据来源: Karger
摘要:
A comprehensive study of haemostasis has been performed in a homogeneous group of 25 adult patients with conservatively treated chronic uraemia. We have found prolonged bleeding time, impaired platelet adhesiveness and aggregation, and decreased platelet factor 3 activity, increased values of fibrinogen, of factor VIII activity and related antigen, and of combined levels of factors II, VII and X. Non-significantly abnormal concentrations of factor XIII and of plasminogen and significantly lower values of plasminogen activators and higher values of urokinase inhibitors and anti-plasmin have also been found. Fibrinogen degradation products were detected in the urine of some patients.
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