Denture stomatitis: The clinical effects of chlorhexidine and amphotericin B
作者:
OlsenIngar,
期刊:
Acta Odontologica Scandinavica
(Taylor Available online 1975)
卷期:
Volume 33,
issue 1
页码: 47-52
ISSN:0001-6357
年代: 1975
DOI:10.3109/00016357509004626
出版商: Taylor&Francis
关键词: stomatitis;antifungal agents;chlorhexidine;amphotericin B
数据来源: Taylor
摘要:
The clinical effects of an antibacterial substance with antifungal activity (chlorhexidine) and a specific antimycotic (amphotericin B) in denture stomatitis were studied in 100 patients. Five 14-day regimens of chlorhexidine, amphotericin B or placebo lozenges combined with denture immersion in 0.2% chlorhexidine or water were tested. The efficiency of amphotericin B and chlorhexidine was comparable. This indicates that chlorhexidine has a considerable antifungal effect in the oral cavity and, further, that fungi are the responsible micro-organisms in denture stomatitis rather than bacteria. Chlorhexidine frequently discoloured the dentures. A high incidence of local and general predisposing factors to denture stomatitis, as well as of relapse 14 days after treatment, was observed.
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