An air-fluidized bed was found to be a potential bacteriologic hazard when used by heavily infected burned patients. Even after following the manufacturer's protocol for eliminating bacteria from the bed and for cleaning the filter sheet,Staphylococcus aureus, Staphylcoccus epidermidis, Streptococcus fecalis, Escherichia coli, andSerratia marcescenswere recovered. Use of the bed was suspended until an effective disinfecting procedure was developed for the filter sheet and weekly removal of solid materials from the bed was instituted.