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Effects of indomethacin on bone ingrowth

 

作者: J. C. Keller,   T. M. Trancik,   F. A. Young,   E. St. Mary,  

 

期刊: Journal of Orthopaedic Research  （WILEY Available online 1989）
卷期: Volume 7, issue 1  

页码: 28-34

 

ISSN:0736-0266

 

年代: 1989

 

DOI:10.1002/jor.1100070105

 

出版商: Wiley Subscription Services, Inc., A Wiley Company

 

关键词: Indomethacin;Bone ingrowth;Porous titanium implant

 

数据来源: WILEY

 

摘要:

AbstractThe effects of indomethacin, a nonsteriodal antiinflammatory agent, on bone ingrowth were studied using a rabbit animal model and a porous cylindrical implant system. Bone ingrowth was found to be independent of pore size in the range tested (0.6–1.0 mm). In the control (placebo‐treated) group, there was a significant increase in bone ingrowth between the 2‐ and 8‐week groups of animals. However, in the indomethacin‐treated group, there was no increase in bone ingrowth

 

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