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THE INFLUENCE OF PRESSURE AND TEMPERATURE ON THE KINETICS OF VACUUM DRYING OF KETOPROFEN

 

作者: D. Skansi,   S. Tomas,   I. Fudic,   A. Arapović,  

 

期刊: Drying Technology  （Taylor Available online 1997）
卷期: Volume 15, issue 5  

页码: 1617-1631

 

ISSN:0737-3937

 

年代: 1997

 

DOI:10.1080/07373939708917312

 

出版商: Taylor & Francis Group

 

关键词: pharmaceutical drying;simulation;quality

 

数据来源: Taylor

 

摘要:

This paper explores the influence of temperature and pressure on drying kinetics of 2-(3-benzoylphenil propionic acid) ketoprofen, in a vacuum dryer on laboratory scale, Experimentally determined relations between moisture content and drying rate vs time, were approximated with an exponential model. Model parameters were correlated with drying conditions (temperature, pressure) and defined by functions of their potentions.

 

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