Persistence of Antibodies to Hepatitis C Virus in a Chronic Hemodialysis Population
作者:
F. Carrera,
J.G. Silva,
C. Oliveira,
J.M. Frazao,
C. Pires,
期刊:
Nephron
(Karger Available online 1994)
卷期:
Volume 68,
issue 1
页码: 38-40
ISSN:1660-8151
年代: 1994
DOI:10.1159/000188084
出版商: S. Karger AG
关键词: Hemodialysis;Hepatitis C virus antibodies;Non-A;non-B hepatitis
数据来源: Karger
摘要:
In order to evaluate the persistence of antibodies against hepatitis C virus (HCV) in a chronic hemodialysis population, we studied 151 HBsAg-negative patients. Anti-HCV titers were evaluated every 3 months over 1 year, and the serum alanine aminotransferase/serum aspartate aminotransferase ratio monthly from the start of hemodialysis. The anti-HCV titers (ELIS A C100-3) remained stable in 127 patients and fluctuated in 24, without an evident correlation with hepatic function. Using our criteria, we found 85 patients with non-A, non-B hepatitis, 57 of them with biochemical criteria of chronic hepatic disease. There was a strong correlation between antibodies to HCV and non-A, non-B hepatitis (χ2; p < 0.05) which was more marked in those patients with biochemical criteria of chronic hepatic disease ( χ2; p < 0.001). We concluded that the anti-HCV titer is reliable as a long-term marker of hepatitis C virus infectio
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