Genetic Epidemiology of the Mitsuda Reaction in Leprosy
作者:
M. Feitosa,
H. Krieger,
I. Borecki,
B. Beiguelman,
D.C. Rao,
期刊:
Human Heredity
(Karger Available online 1996)
卷期:
Volume 46,
issue 1
页码: 32-35
ISSN:0001-5652
年代: 1996
DOI:10.1159/000154322
出版商: S. Karger AG
关键词: Mitsuda reaction;Leprosy;Segregation analysis;Genetic epidemiology
数据来源: Karger
摘要:
This study comprised 544 nuclear families with 2,925 individuals tested for the Mitsuda reaction, from the Campinas region in Brazil. Segregation analyses suggest the segregation of a major gene (χ21 – 0.07 – 0.07 = 0, p = 1), by failing to reject the hypothesis of Mendelian transmission and by rejecting the hypothesis of nontransmission of a major gene (χ23 0.99; χ22 = 198.28 – 0.0 = 198.28, p
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