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Genetic Epidemiology of the Mitsuda Reaction in Leprosy

 

作者: M. Feitosa,   H. Krieger,   I. Borecki,   B. Beiguelman,   D.C. Rao,  

 

期刊: Human Heredity  (Karger Available online 1996)
卷期: Volume 46, issue 1  

页码: 32-35

 

ISSN:0001-5652

 

年代: 1996

 

DOI:10.1159/000154322

 

出版商: S. Karger AG

 

关键词: Mitsuda reaction;Leprosy;Segregation analysis;Genetic epidemiology

 

数据来源: Karger

 

摘要:

This study comprised 544 nuclear families with 2,925 individuals tested for the Mitsuda reaction, from the Campinas region in Brazil. Segregation analyses suggest the segregation of a major gene (χ21 – 0.07 – 0.07 = 0, p = 1), by failing to reject the hypothesis of Mendelian transmission and by rejecting the hypothesis of nontransmission of a major gene (χ23 0.99; χ22 = 198.28 – 0.0 = 198.28, p

 

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