Adaptive mutation: A general phenomenon or special case?
作者:
Spencer Benson,
期刊:
BioEssays
(WILEY Available online 1997)
卷期:
Volume 19,
issue 1
页码: 9-11
ISSN:0265-9247
年代: 1997
DOI:10.1002/bies.950190104
出版商: Wiley Subscription Services, Inc., A Wiley Company
数据来源: WILEY
摘要:
AbstractA recent article by Galitski and Roth(1)characterizes adaptive reversion of chromosomallac−mutations inSalmonella typhimuriumLT2. Using a classical genetic approach they show that adaptive reversion, as characterized by the appearance of late revertant colonies, is an exception rather than a general phenomenon for reversion of nonsense, missense, frameshift and insertion mutations. For certain mutations, however, the number of late revertants exceeds the predicted number. These excess revertants suggest that adaptive mutability is applicable to chromosomal genes as well as to genetic changes involving F plasmids and lysogenic phage
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