Teratogenic effects of aldrin, dieldrin, and endrin in hamsters and mice
作者:
Anna D. Ottolenghi,
Joseph K. Haseman,
Fred Suggs,
期刊:
Teratology
(WILEY Available online 1974)
卷期:
Volume 9,
issue 1
页码: 11-16
ISSN:0040-3709
年代: 1974
DOI:10.1002/tera.1420090104
出版商: Wiley Subscription Services, Inc., A Wiley Company
数据来源: WILEY
摘要:
AbstractSingle oral doses of aldrin, dieldrin, and endrin, 1/2 LD50incorn oil, administered to pregnant golden hamsters on day 7, 8, or 9 of gestationcaused a high incidence of fetal death, congenital anomalies, and growthretardation. The most frequent defects were cleft palate, open eye, andwebbed foot, often occurring in combination. Pregnant CD1 mice given equivalent oral doses of each pesticide on day 9 of gestation showed similar anomalieswithout concurrent increase in fetal mortality or growth impairment.
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