Pharmacologic Effects of Melatonin on Hypothalamic-Adenohypophyseal Function in the Nonhuman Primate
作者:
George P. Chrousos,
Teri Brown,
Barry B. Bercu,
期刊:
Neuroendocrinology
(Karger Available online 1982)
卷期:
Volume 34,
issue 5
页码: 343-346
ISSN:0028-3835
年代: 1982
DOI:10.1159/000123325
出版商: S. Karger AG
关键词: Melatonin;Hypothalamus;Pituitary;Primates
数据来源: Karger
摘要:
The pharmacologic effects of intravenous melatonin on hypothalamic-adenohypophyseal function were studied in male rhesus monkeys (n = 10) and compared to control animals (n = 9–13). Basal and arginine- or L-dopa-stimulated values of growth hormone in melatonin-treated animals were similar to those of control primates. Insulin-stimulated growth hormone secretion was slightly decreased. Melatonin did not affect basal or thyroid stimulating hormone releasing hormone (TRH)-stimulated values of thyroid stimulating hormone (TSH) or prolactin. No effects were seen on basal and gonadotropin releasing hormone (GnRH)-stimulated luteinizing hormone (LH) or follicle stimulating hormone (FSH) secretio
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