One hundred consecutive admissions to an intensive outpatient cocaine treatment clinic in Camden, NJ, were assigned DSM‐III‐R Axis I and II psychiatric diagnoses by means of the SCID. Prevalence rates for non‐substance‐use Axis I disorders were equivalent to expected population base rates. By far the most common diagnoses were on Axis II (73% of subjects), with over one‐third of subjects receiving more than one personality disorder diagnosis, frequently crossing DSM‐III‐R “clusters.” In the distribution of psychopathology, certain gender differences were noted. The authors discuss implications for the clinical management and treatment of cocaine‐addicted individuals in