首页   按字顺浏览 期刊浏览 卷期浏览 Adsorptive Stripping Voltammetric Determination of Albendazole at a Hanging Mercury Dro...
Adsorptive Stripping Voltammetric Determination of Albendazole at a Hanging Mercury Drop Electrode

 

作者: Ali Z. Abu Zuhri,   Amjad I. Hussein,   Mohammad Musmar,   Sami Yaish,  

 

期刊: Analytical Letters  (Taylor Available online 1999)
卷期: Volume 32, issue 15  

页码: 2965-2975

 

ISSN:0003-2719

 

年代: 1999

 

DOI:10.1080/00032719908543020

 

出版商: Taylor & Francis Group

 

关键词: Adsorptive voltammetry;albendazole determination;hanging mercury drop

 

数据来源: Taylor

 

摘要:

Albendazole is determined by differential-pulse adsorptive cathodic stripping voltammetry at a hanging mercury drop electrode using the reduction peak of its copper(II) complex at −0.28V at an accumulation potential 0.0V vs. Ag/AgCl electrode. The optimum conditions of pH, accumulation potential and accumulation time were studied. The calibration graph for the determination of albendazole was linear in the range 3.0X10−8- 9X10−7M with a relative standard deviation of 2.8%. The detection limit was 1.0X10−8M after 180s accumulation at 0.0V. The effect of common excipients and metal ions on the peak height of albendazole was studied. The presence of Cu2+ions forms a stable complex with albendazole which is strongly adsorbed at the mercury electrode surface. The method was applied to the determination of the drug in commercially available dosage forms.

 

点击下载:  PDF (325KB)



返 回