The main peculiarities of constructing set of equipment for analysis of α-autoradiographic images are discussed. Hardware, software and metrological means are analysed. The structure of the equipment is presented providing for inspecting homogeneity of plutonium dioxide distribution by means of α-autoradiography under shop conditions. The software has been written on the basis of “RAFOS” (RT-II) operational system. The basic programming language is “FORTRAN IV”. The necessary components and structure of application programs are discussed. As far as metrological means are concerned, built-in and application devices providing for control of the equipment operating characteristics stability are described.