Retinal degeneration in the delayed amelanotic (DAM) chicken: an electroretinographic study
作者:
FultonAnne B.,
FiteKatherine V.,
BengstonLynn,
期刊:
Current Eye Research
(Taylor Available online 1982)
卷期:
Volume 2,
issue 11
页码: 757-763
ISSN:0271-3683
年代: 1982
DOI:10.3109/02713688209020008
出版商: Taylor&Francis
数据来源: Taylor
摘要:
The retinal function of the delayed amelanotic (DAM) chicken that has progressive retinal degeneration, was investigated electroretinographically (ERG). Subjects showing a gradation of abnormalities of retinal morphology and impairment of visual behaviors were tested. Dark-adapted a-, b-, and c-wave responses to full-field stimuli were studied. In general, the more severe the anatomical abnormalities, the greater the compromise of sensitivity and amplitude of ERG responses. The DAM disease appears to affect c-waves more than a-waves, and a-waves more than b-waves. Dark-adapted responses are affected more than light-adapted responses. In DAM's with moderately to severely impaired visual behaviors, ERG studies should permit analysis of the distal retinal pathophysiology caused by this disease.
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