Allele Frequencies for 20 Microsatellites in a Worldwide Population Survey
作者:
Anna Pérez-Lezaun,
Francesc Calafell,
Eva Mateu,
David Comas,
Elena Bosch,
Jaume Bertranpetit,
期刊:
Human Heredity
(Karger Available online 1997)
卷期:
Volume 47,
issue 4
页码: 189-196
ISSN:0001-5652
年代: 1997
DOI:10.1159/000154412
出版商: S. Karger AG
关键词: DNA polymorphism;Microsatellite;Tetranucleotide short tandem repeat;Allele frequency
数据来源: Karger
摘要:
20 microsatellite polymorphisms: HUMHPRT, HUMD3S1358, HUMTH01, HUMACPP, HUMVWF, HUMD16S310, HUMD4S243, HUMTPO, HUMFES/FPS, HUMF13A1, HUMDHFRP2, HUMD11S2010, HUMD13S767, HUMD9S926, HUMD2S1328, HUMD14S306, HUMD18S848, HUMD5S818, HUMD7S820 and HUMFGA were analyzed in a worldwide survey covering five continents and allele frequencies are given. There is a high heterogeneity in allele frequencies among continents. A neighbor-joining tree based on Fst distance shows a pattern of differentiation that may reflect the role of drift in the development of genetic differences among humans. The variation found between continents confirms the usefulness of tetranucleotide microsatellites in human genetic variation studies.
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