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Neuron specific in vitro cytotoxicity of sera from patients with amyotrophic lateral sclerosis

 

作者: Fred J. Roisen,   Harry Bartfeld,   Hyman Donnenfeld,   Janet Baxter,  

 

期刊: Muscle&Nerve  （WILEY Available online 1982）
卷期: Volume 5, issue 1  

页码: 48-53

 

ISSN:0148-639X

 

年代: 1982

 

DOI:10.1002/mus.880050109

 

出版商: Wiley Subscription Services, Inc., A Wiley Company

 

数据来源: WILEY

 

摘要:

AbstractSera from patients with amyotrophic lateral sclerosis (ALS) were assayed for a neuron‐specific cytotoxic effect on long‐term organized cultures of neonatal mouse anterior horn segments. Blind studies show that ALS sera when incorporated into the culture media have a greater degree of antineuronal toxicity than sera from patients with other neurological diseases or from family members of ALS patie

 

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