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Lack of Acuted-Amphetamine Effects on Thyrotropin Release

 

作者: Karley Y. Little,   James C. Garbutt,   James P. Mayo,   George Mason,  

 

期刊: Neuroendocrinology  （Karger Available online 1988）
卷期: Volume 48, issue 3  

页码: 304-307

 

ISSN:0028-3835

 

年代: 1988

 

DOI:10.1159/000125026

 

出版商: S. Karger AG

 

关键词: Thyrotropin;d-Amphetamine;Norepinephrine

 

数据来源: Karger

 

摘要:

Case reports have suggested that amphetamine abuse causes excessive secretion of thyrotropin (TSH) and thyroxine (T4). Such an amphetamine-induced effect might be noradrenergic-mediated in the hypothalamus. The current controlled study examined oral d-amphetamine effects on the hypothalamic-pituitary-thyroid axis in normal humans. No acute effects were seen on TSH, T3 or T4 levels, d-Amphetamine elevated cortisol levels at 180 min, as previously reported.

 

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