Noradrenaline Content and Release in the Mesenteric Artery of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) and a New Strain of SHRSP (M-SHRSP)
作者:
Keiichi Shimamura,
Tomoko Shimada,
Kazuo Yamamoto,
Satoru Sunano,
Kozo Okamoto,
期刊:
Journal of Vascular Research
(Karger Available online 1987)
卷期:
Volume 24,
issue 6
页码: 334-338
ISSN:1018-1172
年代: 1987
DOI:10.1159/000158710
出版商: S. Karger AG
关键词: Noradrenaline;Mesenteric artery;Hypertensive rats
数据来源: Karger
摘要:
Adrenergic innervation in the main trunk of the mesenteric artery was studied in stroke-prone spontaneously hypertensive rats (SHRSP) as well as in a new strain of SHRSP (M-SHRSP) and was compared with that of normotensive Wistar Kyoto rats (WKY). Noradrenaline (NA) content and high K-induced NA release in the artery of 6-week-old SHRSP and M-SHRSP were greater than those in the artery of WKY. These results suggest that a higher adrenergic innervation of the artery might be involved in the development of hypertension in SHRSP and M-SHRSP.
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