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Induction of superoxide dismutase isozymes in rabbit lung due to aniline exposure

 

作者: Poonam Kakkar,   P. N. Viswanathan,  

 

期刊: Journal of Applied Toxicology  （WILEY Available online 1987）
卷期: Volume 7, issue 1  

页码: 7-13

 

ISSN:0260-437X

 

年代: 1987

 

DOI:10.1002/jat.2550070103

 

出版商: John Wiley&Sons, Ltd.

 

关键词: superoxide dismutase;isozyme;induction;toxicity;aniline;lung oxidants;inhalation;rabbit;free radicals

 

数据来源: WILEY

 

摘要:

AbstractSingle exposure of rabbits to aniline vapors caused induction of superoxide dismutase isozymes and activity as evidenced by the incorporation of radioactive amino acids and prosthetic group metals into enzymatic protein zones of electrophoreograms. Induced of a new cytosolic isozyme following aniline exposure was also evident. Xenobiotic stress indicated a close relation between free radical processes and lung biotransformation mechanisms.

 

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