Simultaneous Determination of 2-Imidazolines and Other Pharmaceutical Substances in Commercial Preparations by High-Performance Liquid-Chromatography
作者:
JohnE. Kountourellis,
Antonia Raptouli,
期刊:
Analytical Letters
(Taylor Available online 1988)
卷期:
Volume 21,
issue 8
页码: 1361-1370
ISSN:0003-2719
年代: 1988
DOI:10.1080/00032718808059869
出版商: Taylor & Francis Group
关键词: 2-imidazolines;antazoline;tetrahydrozoline;naphazoline;tramazoline;xylometazoline;oxymetazoline;dexamethasone;pharmaceutical formulations;HPLC;alumina
数据来源: Taylor
摘要:
A rapid HPLC method has been presented for the determination of some 2-imidazolines in several liquid or semi-solid commercial preparations. Two of the active ingredients were determined simultaneously whereas others were determined in the presence of dexamethasone and excipients. From the sample solutions no interference was observed on the chromatograms. Linearity and precision of the method have been assessed. The assay results obtained for various formulations were in accord with the declared amount.
点击下载:
PDF (298KB)
返 回