EXCHANGE REACTIONS IN METABOLISM
作者:
M.G. Clark,
J.F. Williams,
P.F. Blackmore,
期刊:
Catalysis Reviews
(Taylor Available online 1974)
卷期:
Volume 9,
issue 1
页码: 35-77
ISSN:0161-4940
年代: 1974
DOI:10.1080/01614947408075369
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Recent studies from this laboratory [l, 2] on the reaction mechanism of the pentose phosphate pathway in rabbit and rat liver cells have accentuated the role of enzyme-catalyzed exchange reactions as a means by which tracer carbon is relocated in the absence of a net metabolic flux. While this is an intrinsic property of the group transferring enzymes of the pathway and is seen as a deleterious property of14C for the mapping and quantitation of metabolic pathways, it has re-emphasized the possible usefulness of isotope exchange reactions in understanding the mechanism of action of nature's catalyst.
点击下载:
PDF (1881KB)
返 回