Antifungicidal, antibacterial and antifertility activities of biologically active heterocyclic thiosemicarbazones and their coordination complexes with the dimethylsilicon moiety
作者:
D Singh,
R V Singh,
R B Goyal,
期刊:
Applied Organometallic Chemistry
(WILEY Available online 1991)
卷期:
Volume 5,
issue 1
页码: 45-50
ISSN:0268-2605
年代: 1991
DOI:10.1002/aoc.590050106
出版商: John Wiley&Sons, Ltd.
关键词: heterocyclic thiosemicarbazones;Dimethylsilicon complexes;antifungicidal activity;antibacterial activity;antifertility activity;1H NMR spectra;13C NMR spectra
数据来源: WILEY
摘要:
AbstractSynthetic, structural and biological aspects of trigonal‐bipyramidal, Me2Si(NS)Cl and octahedral, Me2Si(NS)2types of organosilicon (IV) complexes of heterocyclic thiosemicarbazones (NSH) have been described. The complexes were characterized by elemental analysis, molecular weight determination, conductance measurements and electronic, infrared,1H and13C NMR spectral studies. Some ligands and their corresponding dimethylsilicon (IV) complexes have been tested for their effects on several pathogenic fungi and bacteria. Two representative complexes have also been found to act as sterilizing agents by reducing the production of sperm in male m
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